Classy Hatter

Peerless Assassin isn’t much more expensive. I have it on my Ryzen 5700x, and it’s never audible. At idle my PC is pretty much silent and while playing games GPU and case fans hides any noise the PA makes.

This diet is based on Dr. Roy Taylor’s research on Type 2 Diabetes, and its reversal. He and his team noticed that people with T2D have fat in their liver and pancreas. They confirmed this with a new MRI imaging technique that they developed. Regardless of body weight, if you have fatty liver/pancreas you have T2D or at least pre-diabetes. But, if your liver and pancreas are healthy, you can be overweight and not have T2D.

They call it the twin cycle hypothesis. Google it up, but short is this. If fat builds up in your liver, it starts a cycle that among other things causes the liver to send fat in to your pancreas, which starts another cycle in the pancreas, which feeds the liver’s cycle. As the pancreas gets more and more fatty, the insulin producing beta-cells begins to de-activate, which leads to T2D.

They wanted to test whether this hypothesis is true, and if so, is T2D reversible. How to do that? Their T2D test subjects must loose weight. What’s the fastest way to do that? Extreme caloric restriction.

They put their subjects on a diet consisting of 4 doses of meal replacement formula per day (800kcal/day). Their subjects noticed that it’s actually quite easy to stick to that diet after couple days.

The results of their studies is that if people loses enough fat to free their pancreas from fat, their pancreas can heal and return to normal, reversing T2D. But, there is always a but. If T2D has been going for too long (over 6 years in their studies), too many of the beta-cells have died, and full reversal of T2D is not possible.

Note: Extreme caloric restriction is very dangerous if you are on T2D medication. Do your own research and talk to your doctor. I tried to use correct terms so it’s easy to check the things.

This is a good point. Black PSU and motherboard might stand out too much in that light, white-ish case.

I agree with this. Could easily save $200 buying some older and lower spec components. CPU choice is probably because of the iGPU, but there are other cheaper CPUs with iGPU. I don’t think the use case is going to require more computing power in the future, so I don’t know if future proofing is really necessary. If the use case changes some few years from now, you need to buy new components regardless of your choices today. Save some money now and put it towards a future upgrade.

16GB DDR4 is enough. That’s about $40 off. SSD is pointlessly big for the use case. 250GB might be enough, but even 512GB would be a bit cheaper.

CPU could be downgraded to something a couple generations older. Motherboard can also be downgraded, unless that one has some important features. That saves at least $150 total.

PSU is a complicated question. Cheaper would be enough, but you might lose money over time in your electricity bill. That’s kind of difficult to calculate.

Ozempic’s maker is just trying to protect Americans from the harmful side effects with the unconscionably high price.

Depending on your needs, virtual machine might be the easiest solution.

Absolutely bonkers, they were testing that thing so close to population. There are residential areas within about 1km/mile from the test site. In one of the videos, it sounds like the blast wave destroyed some window. So, even if that thing would have only exploded during the test, it would have caused harm in those areas. Luckily, it landed on an empty area.

American Healthcare

Fan Control is great. Like you mentioned, the possibility to create mix fan curves is really helpful. For example, if either CPU or GPU gets hot, you can set all the case fans to ramp up. There are good guide videos on YouTube that shows how to set it up.